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Learn about the 2 mL diluent volume for your hemophilia factor VIII therapy. Less to infuse. Convenient to use. Look for the 2 mL purple package, which includes the BAXJECT II device and a 25 gauge infusion set to accommodate the lower infusion volume. ADVATE [Antihemophilic Factor (Recombinant), Plasma/Albumin-Free Method] is available with 2 mL diluent volume for seven different potencies: 250 IU, 375 IU, 500 IU, 750 IU, 1000 IU, 1500 IU, and 1700 IU. For more information, visit www.advate.com. INFUSION INFORMATION FOR ADVATE You should be trained on how to do infusions by your hemophilia treatment center or your healthcare provider. The maximum infusion rate is 10 mL ADVATE [Antihemophilic Factor (Recombinant), Plasma/Albumin-Free Method] is a medicine used to replace clotting factor VIII that is missing in people with hemophilia A (also called “classic” hemophilia). ADVATE is used to prevent and control bleeding in people with hemophilia A. Your healthcare provider may give you ADVATE when you have surgery. ADVATE is not used to treat von Willebrand Disease. DETAILED IMPORTANT RISK INFORMATION FOR ADVATE You should not use ADVATE if you are allergic to mice or hamsters or any ingredients in ADVATE. You should tell your healthcare provider if you have or have had any medical problems, take any medicines, including prescription and non-prescription medicines and dietary supplements, have any allergies, including allergies to mice or hamsters, are nursing, are pregnant

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